Methanesulfonic Acid → HCID 86758892, compound

Participants

Reaction Steps

To a stirred solution of ethyl 2-[2-chloro-4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]phenoxy]acetate (770 mg) in ethanol (4 ml) was added methanesulfonic acid (79 μl) at room temperature, and the mixture was stirred for 30 minutes. Collection of the resulting precipitates by filtration gave ethyl 2-[2-chloro-4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]phenoxy]acetate methanesulfonate (220 mg).

Provenance & Evidence