Tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilane → HCID 18619663, compound

Participants

Reaction Steps

2-(4-{2-[2-Chloro-4-(3-methyl-1 H-pyrazol-1-yl)phenyl]-3H-imidazo[4,5-b]pyridin-3-yl}phenyl)-1-ethanamine formate (0.212 g, 0.447 mmol) was reacted with tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenyl-silane (0.18 g, 0.44 mmol) according to Procedure G (eluant: 20:1 going to 5:1 chloroform-methanol) to give the title compound (0.18 g, 0.216 mmol).

Provenance & Evidence