Bromine → HCID 20393726, compound

HRID 1862823Notes

Reaction equation

HRID 1862823 reaction equation
[CH:1]([NH:4][C:5]1[C:18]2[C:17](=[O:19])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][C:15]=3[O:20][CH3:21])[C:10](=[O:22])[C:9]=2[CH:8]=[CH:7][CH:6]=1)([CH3:3])[CH3:2].[Br:23]Br>Cl>[CH:1]([NH:4][C:5]1[C:18]2[C:17](=[O:19])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][C:15]=3[O:20][CH3:21])[C:10](=[O:22])[C:9]=2[C:8]([Br:23])=[CH:7][CH:6]=1)([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 24408Bromine2×HCID 20393724HCID 20393724, compound

Product 1

HCID 20393726HCID 20393726, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

50 g of 1-isopropylamino-8-methoxy-anthraquinone are dissolved in 500 ml of 30% strength hydrochloric acid; 33 g of bromine are added dropwise to the clear solution over the course of 15 minutes at 10°-15° and the mixture is stirred for a further 18 hours at room temperature. It is stirred into 5,000 ml of ice-cold water, excess bromine is removed by means of the amount of bisulphite just required, and the product is filtered off, washed until neutral and dried in vacuo. Yield: 62 g. Bromine content: 21.1%.

Workup

  1. customis removed by means of the amount of bisulphite
  2. filtrationthe product is filtered off
  3. washwashed until neutral and
  4. customdried in vacuo

Sources & evidence

ORD record
ord-5f589513dfa141a29abe8baa55764dde
Source dataset
uspto-grants-1979_09
Patent number
US04166822

Reaction notes

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