反应详情

A solution of 5.06 g (0.02 Mole) of 2-p-methoxyphenyl-6-formylbenzoxazole of the formula ##STR33## (melting point: 161.5°-162.5° C.) and 7.50 g (0.02 mole) of 2-(p-methoxyphenyl)-6-(diethylphosphonomethyl)-benzoxazole of the formula ##STR34## (melting point: 85°-88° C.) in 150 ml of dimethyl formamide is heated to 50° C. and 2.1 g of sodium tert.butylate are added in small amounts to the solution over the course of 15 minutes. The reaction mixture is stirred at room temperature overnight, then poured into 400 ml of methanol with stirring. The product is collected by filtration, washed with water and then with 140 ml of methanol, and subsequently recrystallised from chlorobenzene with the addition of fuller's earth, affording 7.1 g (75% of theory) of 1,2-bis-(2-p-methoxyphenyl-benzoxazol-6-yl)-ethylene of the formula ##STR35## in the form of pale yellow crystals with a melting point of over 300° C.

1. stirringwith stirring
2. filtrationThe product is collected by filtration
3. washwashed with water
4. customwith 140 ml of methanol, and subsequently recrystallised from chlorobenzene with the addition of fuller's earth