Dimethylamine → HCID 20392556, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 8.6 g (40 millimoles) of 2-methyl-6-benzyl-pyridin-3-ol N-oxide, 5 g of 30% strength aqueous formaldehyde solution, 5.5 g of 40% strength aqueous dimethylamine solution and 9 ml of water is heated for 2 hours at 80° C. It is then evaporated to dryness, the residue is taken up in chloroform, this solution is shaken with active charcoal and filtered, and the solvent is distilled off. 10.2 g of 2-methyl-4-dimethylaminomethyl-6-benzyl-3-pyridin-3-ol N-oxide remain.

Provenance & Evidence