4-Chlorophenol → HCID 12531883, compound

HRID 1863280Notes

Reaction equation

HRID 1863280 reaction equation
Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=1>CO>[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([O:27][CH:2]([C:7]2[CH:12]=[CH:11][C:10]([O:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:9][CH:8]=2)[C:3]([O:5][CH3:6])=[O:4])=[CH:23][CH:22]=1

Participants

4

Reactant 2

HCID 46844-ChlorophenolHCID 20392609HCID 20392609, compound

Product 1

HCID 12531883HCID 12531883, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Methyl α-bromo-α-[p-(phenoxy)phenyl]acetate (6.42 g) is reacted with 3.21 g of 4-chlorophenol in methanol as in Example 16 to afford a white solid, which is recrystallized from hexane to yield the product, mp 99°-102° C.

Workup

  1. customto afford a white solid, which
  2. customis recrystallized from hexane
  3. customto yield the product, mp 99°-102° C.

Sources & evidence

ORD record
ord-e82c3985e3a24ea1905d4859014315bb
Source dataset
uspto-grants-1979_09
Patent number
US04168385

Reaction notes

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