Phenol → HCID 12531908, compound

Participants

Reaction Steps

Methyl α-bromo-α-[p-(phenoxy)phenyl]acetate (6.42 g) is reacted with 2.35 g of phenol in methanol as in Example 16 to afford 6 g of a yellow liquid after distillation (154° C. at 0.15 mm). A 2.2 g portion is purified by chromatography on silica gel (60 g) with benzene eluent to give the product as a white solid, mp 75.5°-77° C. (from pet. ether).

Provenance & Evidence