Water → HCID 54045193, compound

Participants

Reaction Steps

A solution of bromine (8.0 gm., 0.05 mole) in acetic acid (10 ml.) is added to a mixture of imidazo[1,5-d]-as-triazin-4(3H)-one (6.8 gm., 0.05 mole) and acetic acid (500 ml.). The reaction mixture is stirred for 1 hour, poured into water and extracted with chloroform. The aqueous layer is separated, made slightly alkaline and extracted with ether. Evaporation of the chloroform and the ether layers yields 5.0 gm. of a solid (46.3%). This solid is recrystallized to afford the title product, a cream colored solid, m.p. 244°-245° C.(d).

Provenance & Evidence