HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 136398813, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl carbazate | HCID 80519 | — |
| Reactant | HCID 20391365 | HCID 20391365 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 136398813 | HCID 136398813 | 90.1% |
Reaction Steps
A mixture of 5-methyl-2-(α,α,α-trifluoro-m-tolyl)imidazole-4-carboxaldehyde (20.0 g, 0.0787 mole), methanol (500 ml), methyl carbazate (7.8 g) and glacial acetic acid (0.5 ml) is refluxed overnight. The solution is then concentrated to afford 23.14 g of title product. A sample is recrystallized from methanol-acetone, m.p. 251°-251.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04168964 |
| Source dataset | uspto-grants-1979_09 |
| ORD ID | ord-8d21a9c1d9af4509b0e178cfa6926d6a |
| Source note | uspto-grants-1979_09 |