Dimethylformamide → isopropyl 2-chloro-4-fluoro-5-{1,2,5,7-tetrahydro-1-methyl-2,4-dioxo-thieno[3,4-d]pyrimidin-3(4H)-yl}-benzoate

HRID 186344Notes

Reaction equation

HRID 186344 reaction equation
[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH:7]([CH3:8])[CH3:9])[cH:10][c:11](-[n:15]2[c:16](=[O:25])[nH:17][c:18]3[c:19]([c:20]2=[O:21])[CH2:22][S:23][CH2:24]3)[c:12]([F:14])[cH:13]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH:7]([CH3:8])[CH3:9])[cH:10][c:11](-[n:15]2[c:16](=[O:25])[n:17]([CH3:26])[c:18]3[c:19]([c:20]2=[O:21])[CH2:22][S:23][CH2:24]3)[c:12]([F:14])[cH:13]1

Participants

3

Reactant 2

HCID 6228DimethylformamideHCID 20130635isopropyl 2-chloro-4-fluoro-5-{1,2,5,7-tetrahydro-2,4-dioxothieno[3,4-d]pyrimidin-3(4H)-yl}-benzoate

Product 1

HCID 20130580isopropyl 2-chloro-4-fluoro-5-{1,2,5,7-tetrahydro-1-methyl-2,4-dioxo-thieno[3,4-d]pyrimidin-3(4H)-yl}-benzoate

Sources & evidence

ORD record
ord-012acb55977b49ad82315c0aa2b8d678
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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