反应详情

A solution containing 6.52 g (0.04 mole) of 4-chromanone oxime and 75 ml benzene was stirred and refluxed for 0.50 hrs. using a Dean-Stark apparatus. The solution was cooled to 60° and 6 drops triethylamine and 3.32 g (0.04 mole) allyl isocyanate in 10 ml benzene was added. The solution was stirred and refluxed for 4 hrs., concentrated to dryness, and the residue was recrystallized from 20 ml toluene to give 7.15 g (73%) of the product, m.p. 83°-86°.

1. temperaturerefluxed for 0.50 hrs
2. temperatureThe solution was cooled to 60°
3. stirringThe solution was stirred
4. temperaturerefluxed for 4 hrs
5. concentration, concentrated to dryness
6. customthe residue was recrystallized from 20 ml toluene