ACETAMIDE, 2-AMINO-N-(2,6-DIMETHYLPHENYL)- → HCID 13177105, compound

HRID 1863452Notes

Reaction equation

HRID 1863452 reaction equation
[ClH:1].[C:2](=[NH:7])([O:4]CC)[CH3:3].[NH2:8][CH2:9][C:10]([NH:12][C:13]1[C:18]([CH3:19])=[CH:17][CH:16]=[CH:15][C:14]=1[CH3:20])=[O:11]>C(O)C>[ClH:1].[CH3:20][C:14]1[CH:15]=[CH:16][CH:17]=[C:18]([CH3:19])[C:13]=1[NH:12][C:10]([CH2:9][NH:8][C:9](=[N:8][CH2:3][C:2](=[O:7])[NH:4][C:13]1[C:18]([CH3:19])=[CH:17][CH:16]=[CH:15][C:14]=1[CH3:20])[CH3:10])=[O:11]

Participants

4

Reactant 2

HCID 87833ACETAMIDE, 2-AMINO-N-(2,6-DIMETHYLPHENYL)-HCID 2724290Ethanimidic acid, ethyl ester, hydrochloride (1:1)

Product 1

HCID 13177105HCID 13177105, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4.85 Grams (0.039 mole) of ethyl acetimidate hydrochloride and 7.0 g of 2-amino-2',6'-dimethylacetanilide were dissolved in 75 ml of anhydrous ethanol and stirred at room temperature for two days. The solid which formed was collected on a filter, recrystallized from ethanol, and dried overnight under vacuum at 60° C. M.P. 240°-241° C.

Workup

  1. customThe solid which formed
  2. customwas collected on a filter
  3. customrecrystallized from ethanol
  4. customdried overnight under vacuum at 60° C

Sources & evidence

ORD record
ord-7f6e5176ec1940ddaf0cc34a1f3cf344
Source dataset
uspto-grants-1979_09
Patent number
US04169106

Reaction notes

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