Hydrazine hydrate (1:1) → HCID 55279615, compound

HRID 1863939Notes

Reaction equation

HRID 1863939 reaction equation
Cl[C:2]1[C:7]2[N:8]=[CH:9][NH:10][C:6]=2[CH:5]=[CH:4][N:3]=1.O.[NH2:12][NH2:13]>C(O)C>[NH:12]([C:2]1[C:7]2[N:8]=[CH:9][NH:10][C:6]=2[CH:5]=[CH:4][N:3]=1)[NH2:13]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 53733644-Chloro-1H-imidazo[4,5-c]pyridine

Product 1

HCID 55279615HCID 55279615, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 200 mg (1.3 mmol) of 4-chloro-1H-imidazo[4,5-c]pyridine [J. A. Montgomery and K. Hewson, J. Med. Chem., 8, 708 (1965)], 0.253 mL (261 mg, 5.2 mmol) of hydrazine hydrate, and 5 mL of ethanol was stirred at room temperature overnight. The precipitate was collected on a filter, washed with a little ethanol, and dried to give the title compound as a solid. LC-MS 150 (M+1).

Workup

  1. customThe precipitate was collected on a filter
  2. washwashed with a little ethanol
  3. customdried

Sources & evidence

ORD record
ord-ad0373af7a5b40e58bff3b4319d05aa4
Source dataset
uspto-grants-2009_12
Patent number
US07625888B2

Reaction notes

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