HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 87483712, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 90695481 | HCID 90695481 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 87483712 | HCID 87483712 | — |
Reaction Steps
To 47 mg (0.89 mmol) of tert-butyl{(1R)-1-(2,4,5-trifluorobenzyl)-2-[9-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4′,3′:1,2]pyrido[3,4-d]pyrimidin-3-yl]ethyl}carbamate was added 1.8 mL of 4M HCl in anhydrous dioxane. The mixture was stirred at room temperature for 30 minutes and then concentrated. The residue was washed with diethyl ether and dried to give the title compound as a white solid. LC-MS 429 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625888B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-e1d287dcad2146fb94e045a132434b34 |
| Source note | uspto-grants-2009_12 |