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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1863952Generated: November 1, 2026

Hydrochloric Acid → HCID 87483712, compound

https://huagongshe.com/reaction/1863952

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 90695481HCID 90695481—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 87483712HCID 87483712—

Reaction Steps

To 47 mg (0.89 mmol) of tert-butyl{(1R)-1-(2,4,5-trifluorobenzyl)-2-[9-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4′,3′:1,2]pyrido[3,4-d]pyrimidin-3-yl]ethyl}carbamate was added 1.8 mL of 4M HCl in anhydrous dioxane. The mixture was stirred at room temperature for 30 minutes and then concentrated. The residue was washed with diethyl ether and dried to give the title compound as a white solid. LC-MS 429 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625888B2
Source datasetuspto-grants-2009_12
ORD IDord-e1d287dcad2146fb94e045a132434b34
Source noteuspto-grants-2009_12