HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl[(1r)-1-(2,5-difluorobenzyl)-3-hydrazino-3-oxopropyl]carbamate → Tert-butyl[(1r)-2-(10-chloro-5,6-dihydro[1,2,4]triazolo[4,3-d][1,4]benzoxazepin-3-yl)-1-(2,5-difluorobenzyl)ethyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl[(1r)-1-(2,5-difluorobenzyl)-3-hydrazino-3-oxopropyl]carbamate | HCID 57973777 | — |
| Reactant | 7-Chloro-2,3-dihydro-5-methoxybenzo[F][1,4]oxazepine | HCID 57973792 | — |
| Product | Tert-butyl[(1r)-2-(10-chloro-5,6-dihydro[1,2,4]triazolo[4,3-d][1,4]benzoxazepin-3-yl)-1-(2,5-difluorobenzyl)ethyl]carbamate | HCID 91178718 | — |
Reaction Steps
By the procedure of Example 5, Step A, the title compound was prepared from tert-butyl[(1R)-1-(2,5-difluorobenzyl)-3-hydrazino-3-oxopropyl]carbamate (Intermediate 2) and 7-chloro-5-methoxy2,3-dihydro-1,4-benzoxazepine (Intermediate 15). LC-MS 491 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625888B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-9f3ac25d76af4d1b8e6ab3ee6390e51b |
| Source note | uspto-grants-2009_12 |