HCID 68522763, compound → HCID 57973809, compound

Participants

Reaction Steps

A solution of 26.1 mg (0.067 mmol) of N-[(1R)-2-bis[1,2,4]triazolo[1,5-c:4′,3′-a]pyrimidin-3-yl-1-(2,4,5-trifluorobenzyl)ethyl]acetamide in 3 mL of 6N hydrochloric acid was stirred at reflux under nitrogen for 12 h. The solution was evaporated to dryness, and the residue was purified by preparative thin-layer chromatography on silica gel (90:10:1 dichloromethane:methanol:concentrated ammonium hydroxide) to give the title compound as a white solid. LC-MS 348 (M+1).

Provenance & Evidence