HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Bromobenzyl chloride → 1-Bromo-4-{[(2S)-3-methoxy-2-methylpropoxy]methyl}benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Bromobenzyl chloride | HCID 68528 | — |
| Reactant | (2R)-3-Methoxy-2-methylpropan-1-ol | HCID 56924404 | — |
| Product | 1-Bromo-4-{[(2S)-3-methoxy-2-methylpropoxy]methyl}benzene | HCID 45489674 | — |
Reaction Steps
According to general method E, 1-bromo-4-chloromethyl-benzene [589-17-3] and (R)-3-methoxy-2-methyl-propan-1-ol are used to afford the title compound as a yellow oil. Rf=0.44 (EtOAc-heptane 1:6); Rt=5.29 (gradient I).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625893B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-8cf95cef1454405c80effb01aa4b2b4e |
| Source note | uspto-grants-2009_12 |