HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1864144Generated: November 1, 2026
HCID 11340732, compound → HCID 11429113, compound
https://huagongshe.com/reaction/1864144
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 11340732 | HCID 11340732 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 11429113 | HCID 11429113 | 103.5% |
Reaction Steps
{4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino]-cyclohexyl}-carbamic acid tert-butyl ester (30 mg, 0.06 mmol) was dissolved in 4M HCl in dioxane (2 mL) and then stirred overnight at 40° C. The resulting solution was evaporated to provide compound A54 as a white solid (24 mg, 100%). Exact mass calculated for C18H22N6O2S 386.2, found 387.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07625906B2 |
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| Source dataset | uspto-grants-2009_12 |
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| ORD ID | ord-30cd8699c20d4a4982c8033cdd114ef2 |
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| Source note | uspto-grants-2009_12 |
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