Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1864144Generated: November 1, 2026

HCID 11340732, compound → HCID 11429113, compound

https://huagongshe.com/reaction/1864144

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11340732HCID 11340732—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 11429113HCID 11429113103.5%

Reaction Conditions

Temperature40 °C

Reaction Steps

{4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino]-cyclohexyl}-carbamic acid tert-butyl ester (30 mg, 0.06 mmol) was dissolved in 4M HCl in dioxane (2 mL) and then stirred overnight at 40° C. The resulting solution was evaporated to provide compound A54 as a white solid (24 mg, 100%). Exact mass calculated for C18H22N6O2S 386.2, found 387.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625906B2
Source datasetuspto-grants-2009_12
ORD IDord-30cd8699c20d4a4982c8033cdd114ef2
Source noteuspto-grants-2009_12