HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → HCID 69057020, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | HCID 57501935 | HCID 57501935 | — |
| Product | HCID 69057020 | HCID 69057020 | — |
Reaction Steps
5-(2-Chloroethoxy)-N-[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]quinazolin-4-amine (0.400 g) and ethylamine (1.2 g) were heated at 50° C. overnight and then the solution purified by chromatography using DCM to 10% 7N ammonia in methanol in DCM to give N-[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]-5-[2-(ethylamino)ethoxy]quinazolin-4-amine; Mass spectrum MH+ 450.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625908B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-121a3dfff7ff4caba1911f6a2935b209 |
| Source note | uspto-grants-2009_12 |