HRID1864377

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5238

Sodium Iodide

INa

HCID7672

Phenyl isocyanate

C7H5NO

结构：Cc1ccc(S(=O)(=O)N2CC2C(=O)N2CCN(c3cc(C)ccc3C)CC2)cc1

HCID86623481

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(S(=O)(=O)N2CC(C(=O)N3CCN(c4cc(C)ccc4C)CC3)N(c3ccccc3)C2=O)cc1

HCID25027933

未命名化合物

PROCEDURE

实验过程

In analogy to example 2, [4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-[1-(toluene-4-sulfonyl)-aziridin-2-yl]-methanone was reacted with sodium iodide and phenylisocyanate to give the title compound as a colorless solid. MS: 532.8 ([M+H]+)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f28b529ffe014c7d8016317d553b64e5
来源数据集: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07625902B2
来源说明: uspto-grants-2009_12

反应 SMILES

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([C:15]([CH:17]2[CH2:19][N:18]2[S:20]([C:23]2[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=2)(=[O:22])=[O:21])=[O:16])[CH2:11][CH2:10]1.[I-].[Na+].[C:32]1([N:38]=[C:39]=[O:40])[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[N:9]1[CH2:10][CH2:11][N:12]([C:15]([CH:17]2[CH2:19][N:18]([S:20]([C:23]3[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=3)(=[O:22])=[O:21])[C:39](=[O:40])[N:38]2[C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)=[O:16])[CH2:13][CH2:14]1