Sodium Iodide → HCID 67141199, compound

HRID 1864378Notes

Reaction equation

HRID 1864378 reaction equation
[CH3:1][O:2][C:3]([CH:5]1[CH2:7][N:6]1[S:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[C:17]([F:20])([F:19])[F:18])(=[O:10])=[O:9])=[O:4].[C:21]1([N:27]=[C:28]=[O:29])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.[I-].[Na+]>>[CH3:1][O:2][C:3]([CH:5]1[CH2:7][N:6]([S:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[C:17]([F:18])([F:19])[F:20])(=[O:9])=[O:10])[C:28](=[O:29])[N:27]1[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:4]

Participants

4

Reactant 3

HCID 5238Sodium IodideHCID 7672Phenyl isocyanateHCID 86623482(RS)-1-(2-trifluoromethyl-benzenesulfonyl)-aziridine-2-carboxylic acid methyl ester

Product 1

HCID 67141199HCID 67141199, compound

Procedure

In analogy to example 1, (RS)-1-(2-trifluoromethyl-benzenesulfonyl)-aziridine-2-carboxylic acid methyl ester was reacted with phenylisocyanate and sodiumiodide to give (RS)-2-oxo-3-phenyl-1-(2-trifluoromethyl-benzenesulfonyl)-imidazolidine-4-carboxylic acid methyl ester.

Sources & evidence

ORD record
ord-1676a7ecbe454bf780c738f07968f7f6
Source dataset
uspto-grants-2009_12
Patent number
US07625902B2

Reaction notes

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