Sodium Iodide → HCID 67141117, compound

HRID 1864448Notes

Reaction equation

HRID 1864448 reaction equation
[CH3:1][O:2][C:3]([CH:5]1[CH2:7][N@@:6]1[S:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[Cl:17])(=[O:10])=[O:9])=[O:4].[Cl:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[N:25]=[C:26]=[O:27].[I-].[Na+]>>[CH3:1][O:2][C:3]([C@@H:5]1[CH2:7][N:6]([S:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:17])(=[O:9])=[O:10])[C:26](=[O:27])[N:25]1[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=1[Cl:18])=[O:4]

Participants

4

Reactant 3

HCID 5238Sodium IodideHCID 76833Chlorophenyl isocyanateHCID 178498700HCID 178498700, compound

Product 1

HCID 67141117HCID 67141117, compound

Procedure

In analogy to example 1, step 3, (S)-1-(2-chloro-benzenesulfonyl)-aziridine-2-carboxylic acid methyl ester was reacted with 2-chlorophenylisocyanate and sodium iodide to give (S)-1-(2-chloro-benzenesulfonyl)-3-(2-chloro-phenyl)-2-oxo-imidazolidine-4-carboxylic acid methyl ester as a colorless foam.

Sources & evidence

ORD record
ord-3b6439fda5ac45bbb99af05b1e8ec5bf
Source dataset
uspto-grants-2009_12
Patent number
US07625902B2

Reaction notes

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