Sodium Iodide → 1-(2-Chloro-benzenesulfonyl)-3-isopropyl-4-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one

Participants

Role	Name	HCID	Charge
Reactant	Sodium Iodide	HCID 5238	—
Reactant	Isopropyl isocyanate	HCID 61277	—
Reactant	HCID 178519786	HCID 178519786	—
Product	1-(2-Chloro-benzenesulfonyl)-3-isopropyl-4-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one	HCID 67141111	—

Reaction Steps

In analogy to example 2, [(S)-1-(2-chloro-benzenesulfonyl)-aziridin-2-yl]-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-methanone (example 72, step 3) was reacted with sodium iodide and isopropylisocyanate to give the title compound as a colorless foam. MS: 560.2 ([M+H]+)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07625902B2
Source dataset	uspto-grants-2009_12
ORD ID	ord-13a12e0a583a48baba58076ea951831a
Source note	uspto-grants-2009_12