Lithium Hydroxide → HCID 67141525, compound

HRID 1864469Notes

Reaction equation

C[O:2][C:3]([CH:5]1[CH2:9][N:8]([S:10]([CH:13]([CH3:15])[CH3:14])(=[O:12])=[O:11])[C:7](=[O:16])[N:6]1[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[Cl:23])=[O:4].[OH-].[Li+]>>[Cl:23][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=1[N:6]1[CH:5]([C:3]([OH:4])=[O:2])[CH2:9][N:8]([S:10]([CH:13]([CH3:14])[CH3:15])(=[O:11])=[O:12])[C:7]1=[O:16]

Participants

Reactant 2

HCID 3939Lithium Hydroxide

HCID 67141748HCID 67141748, compound

Product 1

HCID 67141525HCID 67141525, compound

Procedure

In analogy to example 1, (RS)-3-(2-chloro-phenyl)-2-oxo-1-(propane-2-sulfonyl)-imidazolidine-4-carboxylic acid methyl ester was hydrolyzed using lithium hydroxide solution to give (RS)-3-(2-chloro-phenyl)-2-oxo-1-(propane-2-sulfonyl)-imidazolidine-4-carboxylic acid as a colorless solid. MS: 345.0 ([M−H]−)

Sources & evidence

ORD record: ord-0dd92fb9964f4ff3a87abc117c0a0765
Source dataset: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07625902B2

Reaction notes

Loading…