HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 45096892, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 60208241 | HCID 60208241 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 45096892 | HCID 45096892 | — |
Reaction Steps
Ester (2) was stirred in a 50:50 solution of TFA:CH2Cl2 for 1 hour. The solvent was then removed, and the residue was redissolved in methylene chloride and washed with a saturated solution of Na2CO3. The organic layer was then separated and dried over MgSO4 giving desired piperazine compound (3) as a white solid (87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625909B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-cc1a1e3b2fea47c2a517300880cf2161 |
| Source note | uspto-grants-2009_12 |