1,4-Dioxane hydrochloride → HCID 55298731, compound

HRID 1864513Notes

Reaction equation

HRID 1864513 reaction equation
[CH3:1][CH:2]1[CH2:3][N:4](C(OC(C)(C)C)=O)[CH2:5][CH2:6]/[C:7]/1=[N:8]\[O:9][CH3:10].Cl.O1CCOCC1>CO>[CH3:10][O:9]/[N:8]=[C:7]1/[CH:2]([CH3:1])[CH2:3][NH:4][CH2:5][CH2:6]/1

Participants

4

Reactant 2

HCID 204431481,4-Dioxane hydrochlorideHCID 59710395HCID 59710395, compound

Product 1

HCID 55298731HCID 55298731, compoundYield 147.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1,1-Dimethylethyl(4E)-3-methyl-4-[(methyloxy)imino]-1-piperidinecarboxylate (197 mg) was dissolved in methanol, treated with 4.0 N HCl/dioxane (4 mL) and stirred overnight. The reaction was then concentrated to provide the product as a white solid (170 mg). The crude material was used without further purification.

Workup

  1. concentrationThe reaction was then concentrated

Sources & evidence

ORD record
ord-a99f0af5f4f14a0782c2824fd68a3fa1
Source dataset
uspto-grants-2009_12
Patent number
US07625909B2

Reaction notes

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