tert-Butyl (1-benzhydrylazetidin-3-yl)carbamate → 3-Aminoazetidine, 3-BOC protected

Beteiligte Stoffe

Reaktionsschritte

A solution of 1,1-dimethylethyl [1-(diphenylmethyl)-3-azetidinyl]carbamate in MeOH (10 mL) was treated with of 4.0 N HCl/dioxane (1 mL) and then reacted overnight with hydrogen gas at 50 psi. The reaction mixture was then filtered through a pad of Celite, concentrated and the crude residue was used without further purification.

Herkunft & Nachweise