HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyano-3-[4-(2-cyanophenyl)phenyl]-5-ethyl-1-methylpyrrole-2-carboxylic acid → 4-Cyano-3-[4-(2-cyanophenyl)phenyl]-5-ethyl-1-methylpyrrole-2-carboxylic acid dimethylsulfoxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyano-3-[4-(2-cyanophenyl)phenyl]-5-ethyl-1-methylpyrrole-2-carboxylic acid | HCID 11291212 | — |
| Reactant | (Methanesulfinyl)methane--water (1/1) | HCID 23503278 | — |
| Product | 4-Cyano-3-[4-(2-cyanophenyl)phenyl]-5-ethyl-1-methylpyrrole-2-carboxylic acid dimethylsulfoxide | HCID 69023775 | — |
Reaction Steps
4-Cyano-3-[4-(2-cyanophenyl)phenyl]-5-ethyl-1-methylpyrrole-2-carboxylic acid, Form I (300 mg) is slurried at RT in a 1:1 v/v mixture (8 mL) of DMSO-H2O for approximately 22 hours, yielding the title compound as a clumpy, granular solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625932B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-9fbb33d9f9844d16863109bac9518d12 |
| Source note | uspto-grants-2009_12 |