HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl cyanoacetate → Ethyl 4-cyano-3-[4-(3-cyano(2-thienyl))phenyl]pyrrole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl cyanoacetate | HCID 7764 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 2-(4-{2-Cyano-2-[(4-methylphenyl)sulfonyl]vinyl}phenyl)thiophene-3-carbonitrile | HCID 69020631 | — |
| Product | Ethyl 4-cyano-3-[4-(3-cyano(2-thienyl))phenyl]pyrrole-2-carboxylate | HCID 69020346 | — |
Reaction Steps
In a manner analogous to the procedure set forth in example A-239, the title compound is prepared from 2-(4-{2-cyano-2-[(4-methylphenyl)sulfonyl]vinyl}phenyl)thiophene-3-carbonitrile, prepared directly above, ethyl cyanoacetate and 1,8-diazabicyclo[5.4.0]undec-7-ene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625932B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-ff6a01c2b0fb4eb38566a4203d96f2f8 |
| Source note | uspto-grants-2009_12 |