反应详情

A mixture of 20% Pd(OH)2 on carbon (0.7 g) and 1-benzyl-4-methylamino-3-ethyl-3-methyl piperidine (6 g, 24.39 mmol) in methanol (60 ml) was stirred in hydrogen atmosphere (1 atm.) at 60° C. for 6 hr. The catalyst was filtered off, washed with methanol and filtrate was concentrated to dryness to afford 4-methylamino-3-ethyl-3-methylpiperidine. Yield 2.5 g (66%), C9H20N2, m/z 157 (M+1).

1. filtrationThe catalyst was filtered off
2. washwashed with methanol and filtrate
3. concentrationwas concentrated to dryness