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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1865781Generated: November 1, 2026

Phosphorus oxychloride → 4-Chloro-1H-pyrazolo[3,4-d]pyrimidine

https://huagongshe.com/reaction/1865781

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178518059HCID 178518059—
Product4-Chloro-1H-pyrazolo[3,4-d]pyrimidineHCID 221095—

Reaction Steps

4-Chloro-1H-pyrazolo[3,4-d]pyrimidine was synthesized from 4-hydroxypyrazolo[3,4-d]pyrimidine and POCl3 as described by R. Robins in J. Am. Chem. Soc., 1957, V. 79, N20, P. 6407-6415.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07629320B2
Source datasetuspto-grants-2009_12
ORD IDord-6aa3df71c00a4d14bcd8dcd8e31989f4
Source noteuspto-grants-2009_12