HuagongsheHuagongshe Chemistry Print Report · For research reference only
3H-spiro(isobenzofuran-1,4'-piperidin)-3-one → 1'-[(1-Benzyl-2-methyl-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3H-spiro(isobenzofuran-1,4'-piperidin)-3-one | HCID 9834255 | — |
| Reactant | 1-Benzyl-2-methyl-1H-indole-3-carboxylic acid | HCID 66743481 | — |
| Product | 1'-[(1-Benzyl-2-methyl-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 15952710 | — |
Reaction Steps
Following the general procedure I as described above, the acylation of 3H-spiro[2-benzofuran-1,4′-piperidin]-3-one prepared as described in example 16 above with 1-benzyl-2-methyl-1H-indole-3-carboxylic acid (preparation described in example 1), gave the title compound. ES-MS m/e (%): 451.6 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629353B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-fabc7af53dd0426c855b3302433ae64c |
| Source note | uspto-grants-2009_12 |