HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 4-Phenyl-1-(4-phenylbutyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Product | 4-Phenyl-1-(4-phenylbutyl)piperidine | HCID 3035672 | — |
Reaction Steps
4-Phenylpiperidine (1 eq) was reacted with 4-phenylbromobutyl (1 eq) in the presence of K2CO3 in acetonitrile at reflux overnight. The product obtained was treated and purified on a silica column. The 1H NMR at 500 MHz is in accordance with the expected structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07629359B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-793b3f195d3042fe9748f4524731fa35 |
| Source note | uspto-grants-2009_12 |