反应详情

A solution of 2-amino-2-ethylbutanoic acid (3.00 g, 22.9 mmol) in MeOH (200 mL) was saturated with HCl (g). The resulting mixture was heated at reflux for 24 h, during which time it was allowed to cool to ambient temperature and was again saturated with HCl (g) twice. After 24 h at reflux, the cooled mixture was concentrated in vacuo to provide the title compound. MS: m/z=146 (M+1).

1. temperatureThe resulting mixture was heated
2. temperatureat reflux for 24 h, during which time it
3. temperatureAfter 24 h at reflux
4. concentrationthe cooled mixture was concentrated in vacuo