HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19029125, compound → 4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19029125 | HCID 19029125 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine | HCID 19029146 | 100.4% |
Reaction Steps
A suspension of 100 mg (0.33 mmol) of 4-(5-methyl-[1,3,4]oxadiazol-2-yl)-piperidine-1-carboxylic acid benzyl ester in 5 ml EtOAc and 10 mg Pd/C 10% was hydrogenated (1 atm) for 1 h. The reaction was filtered (Celite) and evaporated to give 55.4 mg (99%) of the title compound as white solid. MS: 167.9 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632829B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-5c51b251093249d28cbae4a9124eacd3 |
| Source note | uspto-grants-2009_12 |