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HRID1867411

反应详情

EQUATION

反应方程式

HRID 1867411 的结构方程式

REACTANTS

反应物

3
结构：[I-].[Na+]
HCID5238

Sodium Iodide

INa

结构：C1COCCN1
HCID8083

Morpholine

C4H9NO

结构：O=C(/C=C/c1ccc(Cl)c(Cl)c1)N1CCC(=O)N(CCCI)CC1
HCID68433156

未命名化合物

PRODUCTS

生成物

1
结构：O=C(/C=C/c1ccc(Cl)c(Cl)c1)N1CCC(=O)N(CCCN2CCOCC2)CC1
HCID68434905

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 5D, 1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-4-(3-iodo-propyl)-[1,4]diazepan-5-one and morpholine (with no additional sodium iodide) gave after flash silica gel column purification (CH2Cl2/EtOAc 99:1 to 96:4) the title compound as a light yellow viscous oil. MS: 440.2 (MH+, 2Cl).

WORKUP

后处理

  1. customgave
  2. customafter flash silica gel column purification (CH2Cl2/EtOAc 99:1 to 96:4) the title compound as a light yellow viscous oil