huagongshe.com
HRID1867413

反应详情

EQUATION

反应方程式

HRID 1867413 的结构方程式

REACTANTS

反应物

3
结构：O=C(O)/C=C/c1cccc(C(F)(F)F)c1
HCID719451

2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-, (2E)-

C10H7F3O2

结构：O=C1CCN(C(=O)/C=C/c2ccc(Cl)c(Cl)c2)CCN1
HCID62044921

未命名化合物

结构：Cl.Cl.O=C1CCNCCN1CCCN1CCCCC1
HCID67080747

未命名化合物

2 次

PRODUCTS

生成物

1
结构：O=C(/C=C/c1cccc(C(F)(F)F)c1)N1CCC(=O)N(CCCN2CCCCC2)CC1
HCID68434413

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in intermediate 1A, (E)-3-(trifluoromethyl)cinnamic acid and 4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one-dihydrochloride (intermediate 4B, suspended in CH2Cl2 with 4 equivalent of Et3N) gave after purification on catridges, Si-Amine, 70 mL, 20 g (EtOAc) the title compound as a light yellow viscous oil. MS: 438.4 (MH+).

WORKUP

后处理

  1. customgave
  2. customafter purification on catridges, Si-Amine, 70 mL, 20 g (EtOAc) the title compound as a light yellow viscous oil