HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1867415Generated: October 27, 2026
Sodium Iodide → 1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-4-(4-iodo-butyl)-[1,4]diazepan-5-one
https://huagongshe.com/reaction/1867415
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 4-(4-Chloro-butyl)-1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-one | HCID 68435190 | — |
| Product | 1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-4-(4-iodo-butyl)-[1,4]diazepan-5-one | HCID 68433016 | — |
Reaction Steps
In analogy to the procedure described in example 6D, 4-(4-chloro-butyl)-1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-one and sodium iodide were stirred at 90° C. for 26 h to give the title compound as orange foam. MS: 495.0 (MH+, 2Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07632829B2 |
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| Source dataset | uspto-grants-2009_12 |
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| ORD ID | ord-fd0250e75bc74e1eb188273e06126747 |
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| Source note | uspto-grants-2009_12 |
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