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HRID1867440

反应详情

EQUATION

反应方程式

HRID 1867440 的结构方程式

REACTANTS

反应物

2
结构：O=C1CCN(C(=O)/C=C/c2ccc(Cl)c(Cl)c2)CCN1
HCID62044921

未命名化合物

2 次

结构：CC1(C)OC[C@@H](CCOS(C)(=O)=O)O1
HCID86615867

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)OC[C@@H](CCN2CCN(C(=O)/C=C/c3ccc(Cl)c(Cl)c3)CCC2=O)O1
HCID68431987

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described for example 167A, 1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-one (intermediate 1A]) and methanesulfonic acid 2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl ester (prepared from 2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol and methanesulfonyl chloride) gave after reaction at RT, the title compound as an off-white foam. MS: 441.1 (MH+, 2Cl).

WORKUP

后处理

  1. customgave
  2. customafter reaction at RT