HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Z)-3-(Naphthalen-1-yl)acrylic acid → 1-((z)-3-Naphthalen-1-yl-acryloyl)-4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Z)-3-(Naphthalen-1-yl)acrylic acid | HCID 12158295 | — |
| Reactant | 4-(3-Piperidin-1-yl-propyl)-[1,4]diazepan-5-one dihydrochloride | HCID 67080747 | — |
| Product | 1-((z)-3-Naphthalen-1-yl-acryloyl)-4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one | HCID 68432274 | — |
Reaction Steps
In analogy to the procedure described for example 11A, 4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one-dihydrochloride (intermediate 4B) and (Z)-3-naphthalen-1-yl-acrylic acid gave the title compound as light yellow foam. MS: 420.1 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632829B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-b7bde924226e45bf9b6fd528a2151f88 |
| Source note | uspto-grants-2009_12 |