HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1867444Generated: October 25, 2026
Sodium Iodide → 1-(3-Iodo-2,2-dimethyl-propyl)-piperidine
https://huagongshe.com/reaction/1867444
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Methanesulfonic acid 2,2-dimethyl-3-piperidin-1-yl-propyl ester | HCID 86615874 | — |
| Product | 1-(3-Iodo-2,2-dimethyl-propyl)-piperidine | HCID 68434742 | — |
Reaction Steps
In analogy to the procedure described for example 6D, methanesulfonic acid 2,2-dimethyl-3-piperidin-1-yl-propyl ester and sodium iodide stirred at 95° C. for 3 h gave the title compound as brown oil. MS: 282.1 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07632829B2 |
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| Source dataset | uspto-grants-2009_12 |
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| ORD ID | ord-4f65ec02b6aa4616bec9116aca37b182 |
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| Source note | uspto-grants-2009_12 |
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