Sodium Iodide → 1-(3-Iodo-2,2-dimethyl-propyl)-piperidine

HRID 1867444Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1867444
[CH3:1][C:2]([CH3:16])([CH2:9][N:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1)[CH2:3]OS(C)(=O)=O.[I-:17].[Na+]>>[I:17][CH2:3][C:2]([CH3:16])([CH3:1])[CH2:9][N:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1

Komponenten

3

Edukt 2

HCID 5238Sodium IodideHCID 86615874Methanesulfonic acid 2,2-dimethyl-3-piperidin-1-yl-propyl ester

Produkt 1

HCID 684347421-(3-Iodo-2,2-dimethyl-propyl)-piperidine

Reaktionsbedingungen

Temperatur
95 °C

Versuchsvorschrift

In analogy to the procedure described for example 6D, methanesulfonic acid 2,2-dimethyl-3-piperidin-1-yl-propyl ester and sodium iodide stirred at 95° C. for 3 h gave the title compound as brown oil. MS: 282.1 (MH+).

Quellen und Nachweise

ORD-Eintrag
ord-4f65ec02b6aa4616bec9116aca37b182
Quelldatensatz
uspto-grants-2009_12
Patentnummer
US07632829B2

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