HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroethyl isocyanate → HCID 68566485, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroethyl isocyanate | HCID 16035 | — |
| Reactant | 4-Amino-1-Boc-piperidine | HCID 1268291 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68566485 | HCID 68566485 | 116.1% |
Reaction Steps
A solution of 4-amino-1-t-butoxycarbonylpiperidine (200 mg, 1.0 mmol) in tetrahydrofuran (5 mL) was treated with 2-chloroethyl isocyanate (0.090 mL, 1.0 mmol) overnight. The solvent was evaporated to provide the title compound as a white solid (305 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632832B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-abf51cf21fe442d4938cbf3b8fb835b8 |
| Source note | uspto-grants-2009_12 |