HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68565701, compound → HCID 57979565, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68565701 | HCID 68565701 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 57979565 | HCID 57979565 | 89.7% |
Reaction Steps
10% palladium on carbon (10 mg) was added to a solution of 4-benzyl-1-(1-benzylpiperidin-4-yl)imidazolidin-2-one (30 mg, 0.086 mmol) in ethanol (15 mL) and concentrated hydrochloric acid (0.05 mL). The reaction vessel was evacuated and back-filled with nitrogen (3×), then back-filled with hydrogen (40 psi). After 16 h, the mixture was filtered and concentrated to give the title compound (20 mg). MS 260.3 (M+1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632832B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-c8c9761e6bd44d6fb873bf290981dcf8 |
| Source note | uspto-grants-2009_12 |