HRID1867620

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CCOC(=O)/C(=N\O)c1ccccn1$

HCID135741730

未命名化合物

PRODUCTS

生成物

HCID4570669

Ethyl 2-amino-2-(pyridin-2-yl)acetate

C9H12N2O2

收率 103.9%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

10% Palladium on carbon (100 mg) was added to a solution of ethyl (2Z)-(hydroxyimino)(pyridin-2-yl)ethanoate (592 mg, 2.67 mmol) in ethanol (20 mL). The reaction vessel was evacuated and back-filled with nitrogen (3×), then back-filled with hydrogen (1 atm). After 3 h, the mixture was filtered and concentrated to give the title compound (500 mg). MS 181.17 (M+1)

WORKUP

后处理

customThe reaction vessel was evacuated
additionback-filled with nitrogen (3×)
additionback-filled with hydrogen (1 atm)
filtrationthe mixture was filtered
concentrationconcentrated