Ethyl 2-(N-hydroxyimino)-2-(pyridin-2-yl)acetate → Ethyl 2-amino-2-(pyridin-2-yl)acetate

Participants

Reaction Steps

10% Palladium on carbon (100 mg) was added to a solution of ethyl (2Z)-(hydroxyimino)(pyridin-2-yl)ethanoate (592 mg, 2.67 mmol) in ethanol (20 mL). The reaction vessel was evacuated and back-filled with nitrogen (3×), then back-filled with hydrogen (1 atm). After 3 h, the mixture was filtered and concentrated to give the title compound (500 mg). MS 181.17 (M+1)

Provenance & Evidence