4-Toluenesulfonyl chloride → HCID 17962356, compound

HRID 1867919Notes

Reaction equation

HRID 1867919 reaction equation
C([O:4][CH:5]1[CH2:10][CH2:9][O:8][C:6]1=[O:7])(=O)C.[S:11](Cl)([C:14]1[CH:20]=[CH:19][C:17]([CH3:18])=[CH:16][CH:15]=1)(=[O:13])=[O:12]>>[S:11]([O:4][CH:5]1[CH2:10][CH2:9][O:8][C:6]1=[O:7])([C:14]1[CH:20]=[CH:19][C:17]([CH3:18])=[CH:16][CH:15]=1)(=[O:13])=[O:12]

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 10313197HCID 10313197, compound

Product 1

HCID 17962356HCID 17962356, compound

Procedure

reacting enantiopure (S) or (R) α-hydroxy-γ-butyrolactone with tosyl chloride to give enantiopure (S) or (R) α-tosyloxy-γ-butyrolactone (Step 5);

Sources & evidence

ORD record
ord-d703718eb71d497db5c61255c9a781da
Source dataset
uspto-grants-2009_12
Patent number
US07632948B2

Reaction notes

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