HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 2781528, compound → HCID 10480877, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 2781528 | HCID 2781528 | — |
| Reactant | HCID 57982687 | HCID 57982687 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 10480877 | HCID 10480877 | 14.4% |
Reaction Steps
2-Chloro-4-trifluoromethyl-pyrimidin-5-carboxylic acid (tetrahydropyran-4-ylmethyl)-amide (50 mg), 2-methylthio-3-(trifluoromethyl)aniline (125 mg, ex Maybridge) and acetonitrile (0.5 ml) were heated at 190° under microwave irradiation for 30 minutes. The solvent was evaporated in vacuo and the residue purified by mass-directed autopreparation technique, to give the title compound (11 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07635701B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-f1d818141fbe431d9e1d16854cb98991 |
| Source note | uspto-grants-2009_12 |