HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → 2-(3-Chlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclopropylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | 2-(3-Chlorophenylamino)-4-trifluoromethylpyrimidine-5-carboxylic acid | HCID 16719655 | — |
| Product | 2-(3-Chlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclopropylamide | HCID 10406012 | 81.4% |
Reaction Steps
In a manner similar to Reference Example 1 (c) 2-(3-chlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid (35 mg) and cyclopropylamine (9 mg, ex Lancaster) afforded the title compound (32 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07635701B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-2b56ecdc407d49529b251dedd39dafbe |
| Source note | uspto-grants-2009_12 |