HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-3-methoxyaniline → HCID 57982667, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-3-methoxyaniline | HCID 13103692 | — |
| Reactant | 2-Chloro-trifluoromethyl-pyrimidine-5-carboxylic acid cyclohexylmethyl-amide | HCID 57982581 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 57982667 | HCID 57982667 | 47.9% |
Reaction Steps
In a manner similar to Example 243, 2-chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclohexylmethyl-amide (Example 166a) (50 mg) in 1,4-dioxan (1 ml) and 4-chloro-3-methoxy-phenylamine (Wychem) (122 mg) were reacted to give the title compound (33 mg)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07635701B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-89aee481e87b44c6bfd85b4953a8ccb3 |
| Source note | uspto-grants-2009_12 |